Yeo Lab

Degrees

Ph.D.
B.S., Biology and Music, Emory University, 2008

Summary

As an undergraduate at UC Berkeley Anne worked in the lab of Dr. Peggy Lemaux on a projected funded by the Bill and Melinda Gates Foundation aiming to improve the nutritional quality of sorghum plants. With a desire to study human biology and cancer she moved to UCLA for two years in the lab of Amander Clark studying germ cell development and tumor formation using mammalian stem cells. Anne moved to UC San Diego for graduate school with the aim to further develop her expertise in human development and tumorigenesis using stem cells as a model system. Her research in the Yeo Lab uses CLIP-seq and RNA-seq to study regulation by RNA-binding proteins and their roles in cancer and human development. Anne participated in the Genetics Training Program and completed her PhD in the Biomedical Sciences Graduate Program in 2014.

Publications

Kim Y, Deshpande A, Dai Y, Kim JJ, Lindgren A, Conway A, Clark AT, Wong DT. Cyclin-dependent kinase 2-associating protein 1 Commits Murine Embryonic Stem Cell Differentiation through Retinoblastoma Protein Regulation. J Biol Chem. June 2009. Epub ahead of print.

Park TS, Galic Z, Conway AE, Lindgren A, van Handel BJ, Magnusson M, Richter L, Teitell MA, Mikkola HK, Lowry WE, Plath K, Clark AT. Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells. Stem Cells. April 2009.

Karumbayaram S, Novitch BG, Patterson M, Umbach JA, Richter L, Lindgren A, Conway AE, Clark AT, Goldman SA, Plath K, Wiedau-Pazos M, Kornblum HI, Lowry WE. Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells. April 2009.

Xie W, Song C, Young NL, Sperling AS, Xu F, Sridharan R, Conway AE, Garcia BA, Plath K, Clark AT, Grunstein M. Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Molecular Cell. February 2009.

Conway, AE., Lindgren, A., Galic, Z., Pyle, D., Wu, H., Zack, J., Pelligrini, M., Teitell, MA., Clark, AT. A self-renewal program controls the expansion of genetically unstable cancer stem cells in pluripotent stem cell-derived tumors. Stem Cells. January 2009.