Yeo Lab

Degrees

B.S., Biology and Music, Emory University, 2008
Ph.D, Biological Sciences, UC San Diego, 2014

Summary

Thomas previously worked in Guy Benian‘s laboratory at Emory University, studying assembly and maintenance of the muscle contractile apparatus in Caenorhabditis elegans. He also spent a summer in the lab of Alex Andrianopoulos at the University of Melbourne in Australia, which involved analysis of the human pathogen Penicillium marneffei and its ability to alternate between a unicellular and multicellular form. As a graduate student, Thomas is interested in taking a closer look at virus-host interactions with respect to RNA-binding proteins. As part of a collaboration with the Spector lab at UCSD, he plans to initiate these studies using large-scale sequencing methods. Additionally, Thomas is interested in studying elements that allow for productive viral infection of permissive host cell types. Thomas is supported by the Genetics Training Grant at UCSD.

Publications

Virus-Cell Interactions Human Cytomegalovirus Infection of Human Embryonic Stem Cell-Derived Primitive Neural Stem Cells Is Restricted at Several Steps but Leads to the Persistence of Viral DNA Belzile JP, Stark TJ, Yeo GW, Spector DH. Journal of Virology, 2014 [JIV]

The Period protein homolog LIN-42 negatively regulates microRNA biogenesis in C. elegans Van Wynsberghe PM, Finnegana EF, Stark T, Angelus EP, Homan KE, Yeo GW, Pasquinelli AE. ScienceDirect, 2014 [ScienceDirect]

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges. Lovci MT, Ghanem D, Marr H, Arnold J, Gee S, Parra M, Liang TY, Stark TJ, Gehman LT, Hoon S, Massirer KB, Pratt GA, Black DL, Gray JW, Conboy JG, Yeo GW. Nature Structural and Molecular Biology, 2013

LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance. Wilbert MW, Huelga SC, Kapeli K, Stark TJ, Liang TY, Chen SX, Yan BY, Nathanson JL, Hutt KR, Lovci MT, Kazan H, Vu AQ, Massirer KB, Morris Q, Hoon S, Yeo GW. Molecular Cell, 2012. [Mol Cell]

High-resolution profiling and analysis of viral and host small RNAs during human cytomegalovirus infection. Stark TJ, Arnold JD, Spector DH, Yeo GW. J Virol. 2012 [PMID: 22013051]

Miller R, Qadota H, Stark T, Mercer K, Wortham T, Anyanful A, Benian G (2009). CSN-5, a Component of the COP9 Signalosome Complex, Regulates the Levels of UNC-96 and UNC-98, Two Components of M-lines in C. elegans Muscle.Mol. Biol. Cell 15, 3608-3616. [PMID: 19535455]

Qadota H, McGaha L, Mercer K, Stark T, Ferrara T, Benian G (2008). A Novel Protein Phosphatase is a Binding Partner for the Protein Kinase Domains of UNC-89 (Obscurin) in Caenorhabditis elegans. Mol. Biol. Cell 19, 2424-2432. [PMID: 18337465]